Collagenous Intestinal Disorder (CID): Signs, Remedies, and Nutritional Guidelines
Collagenous colitis, a rare intestinal disorder, primarily affects adults over the age of 50, and women are more likely to be diagnosed with the condition. Smoking, certain medications, having an autoimmune condition, and a family history of autoimmune conditions or colitis can also increase the risk of developing collagenous colitis [1].
A gastroenterologist typically diagnoses and manages collagenous colitis, starting with a physical examination, inquiries about the individual's family and medical history, lifestyle habits, eating patterns, smoking history, and medications. A colon biopsy, performed during a colonoscopy or sigmoidoscopy, is required to confirm the diagnosis [2].
The symptoms of collagenous colitis can be uncomfortable and may lead to dehydration and malnutrition, but they do not increase the risk of colon cancer. Common symptoms include chronic watery, nonbloody diarrhea or loose stool, abdominal pain or cramping, fecal incontinence, weight loss, nausea and vomiting, fatigue, bloating and gas, dehydration, anemia, and visible anemia in some cases [3].
Once diagnosed, several treatment options are available. Budesonide is often an effective first-line therapy for collagenous colitis [4]. Other prescription medications used to treat the condition include antidiarrheal medications, supplements to increase the bulk of stool, statin alternatives, mesalamine, antibiotics, immunomodulatory or anti-tumor necrosis factor therapies [1].
It's essential for individuals with collagenous colitis to consult a doctor or dietitian to find the best approach for their condition. Dietary changes, such as avoiding caffeine, artificial sugars, dairy products (if lactose intolerant), foods containing gluten, and drinking plenty of liquids, may help with easing symptoms and reducing the risk of complications [5].
The FDA's recent recommendation to remove ranitidine (Zantac) from the market due to concerns about potential carcinogenic content has led to a need for alternatives for treating acid-related disorders. H2 receptor blockers like famotidine (Pepcid) and cimetidine (Tagamet) are still available, as well as proton pump inhibitors such as omeprazole (Prilosec), lansoprazole (Prevacid), and esomeprazole (Nexium). Antacids like Tums, Rolaids, and Mylanta can provide quick relief from symptoms, but they might not be as effective in severe cases or long-term management. Lifestyle changes, such as reducing the intake of spicy and acidic foods, avoiding smoking, eating smaller meals, and avoiding late-night eating, can also help [6].
The exact cause of collagenous colitis is not fully understood, but it is thought to have a genetic basis and may be linked with other autoimmune diseases. Proposed causes include genetic abnormalities, autoimmune conditions, bile acid misabsorption, bacterial, viral, and fungal infections, smoking, certain medications, and other factors [1].
In conclusion, while collagenous colitis can be a challenging condition to manage, a combination of medical treatment, dietary changes, and lifestyle adjustments can help individuals live comfortably with the disorder. It's crucial to consult a healthcare professional for personalised advice and treatment.
[1] Collagenous colitis: symptoms, causes, and treatment. (2021). Medical News Today. Retrieved from https://www.medicalnewstoday.com/articles/323607 [2] What is a colon biopsy? (2021). Mayo Clinic. Retrieved from https://www.mayoclinic.org/tests-procedures/colon-biopsy/about/pac-20385253 [3] Collagenous colitis: symptoms. (2021). NHS. Retrieved from https://www.nhs.uk/conditions/collagenous-colitis/symptoms/ [4] Collagenous colitis: treatment. (2021). NHS. Retrieved from https://www.nhs.uk/conditions/collagenous-colitis/treatment/ [5] Dietary changes for collagenous colitis. (2021). Healthline. Retrieved from https://www.healthline.com/health/collagenous-colitis/dietary-changes [6] Ranitidine (Zantac) recalled: FDA issues warning. (2019). Mayo Clinic. Retrieved from https://www.mayoclinic.org/diseases-conditions/gastroesophageal-reflux-disease/in-depth/ranitidine/art-20661337 [7] Alternatives to ranitidine (Zantac) for acid reflux. (2021). Medical News Today. Retrieved from https://www.medicalnewstoday.com/articles/3236079 [8] Collagenous colitis: causes. (2021). NHS. Retrieved from https://www.nhs.uk/conditions/collagenous-colitis/causes/
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- In addition to medication and lifestyle changes, individuals with collagenous colitis or other medical-conditions may benefit from support groups focused on mental-health, promoting empathy and camaraderie among those battling similar struggles.
- As the understanding of health-and-wellness continues to grow, it's essential to prioritize knowledge, self-care, and seeking professional guidance in maintaining and improving our overall well-being.