Lynne E. Maquat Wins 2021 Wolf Prize in Medicine for Pioneering RNA Biology Work
Lynne E. Maquat, Ph.D., has been awarded the prestigious 2021 Wolf Prize in Medicine for her pioneering work in RNA biology. The award recognizes her fundamental discoveries, particularly her breakthrough research on nonsense-mediated mRNA decay (NMD).
Maquat's groundbreaking work began in 1980 at the University of Rochester. Her 1981 manuscript unveiled the role of NMD in human cells and its potential to cause disease. NMD acts as a major surveillance system, safeguarding against errors in gene expression that could lead to disorders.
Her research has opened avenues for RNA-based therapeutics, offering hope for various conditions. Maquat's contributions have been recognized with numerous accolades, including the Wiley Prize in Biomedical Sciences (2018) and the Canada Gairdner International Award (2015). She has also been inducted into esteemed institutions such as the National Academy of Medicine (2017), the National Academies of Sciences (2011), and the American Academy of Arts and Sciences (2006).
The Wolf Prize in Medicine, based in Israel where Maquat's journey began, is a testament to her outstanding achievements. She shares this year's award with Joan Steitz, Ph.D., and Adrian Krainer, Ph.D., both recognized for their contributions to RNA biology. Maquat's work continues to pave the way for advancements in the field, benefiting mankind.
