Prescription Drug Dosage Information: Form, Potencies, Administration, and Additional Details on Invokana
Invokana, a medication used to manage blood sugar levels in adults with type 2 diabetes, comes in two strengths: 100 milligrams (mg) and 300 mg. This sodium-glucose co-transporter 2 inhibitor is also prescribed to reduce the risk of heart attack, stroke, and death in people with cardiovascular disease, and to lessen the risk of complications in people with diabetic nephropathy with albuminuria.
The recommended dosage of Invokana is based on the estimated glomerular filtration rate (eGFR). For most patients, the starting dose is 100 mg, taken by mouth before the first meal of the day, once per day. However, for those with decreased kidney function, specifically with an eGFR corresponding to stage 3b chronic kidney disease, the recommended dosage adjustment is to reduce the dose from 300 mg once daily to a maximum of 100 mg once daily. This reduced dose should be continued to maintain kidney and cardiovascular benefits.
It's important to note that for patients with impaired renal function, clinicians should monitor kidney function regularly. If kidney function declines further or other contraindications arise, dosage modifications or complete discontinuation may be necessary.
For patients taking a drug that's a UDP-glucuronosyltransferase (UGT) enzyme inducer, your doctor may increase your Invokana dosage. Conversely, if you have kidney problems, your doctor may prescribe a smaller dose of Invokana.
Invokana is meant to be taken as a long-term treatment. If you miss a dose, take it as soon as you remember, but do not take two doses at the same time to make up for a missed dose. It usually takes a week or so for blood sugar levels to decrease after starting Invokana.
However, if you believe you've taken too much Invokana, call your doctor right away. Invokana is a brand-name prescription medication for adults with type 2 diabetes and is not available in a generic version.
For more information about Invokana, refer to additional articles such as "More about Invokana", "Side effects", and "Details on type 2 diabetes". Always follow the dosage that your doctor prescribes for you, and never change your dosage without your doctor's recommendation.
Deciders of medical-conditions, such as doctors, should consider a patient's kidney function and UDP-glucuronosyltransferase (UGT) enzyme status when prescribing Invokana. This drug, used to manage type 2 diabetes, reduces the risk of heart attack, stroke, and death in specific patients, and it also helps people with diabetic nephropathy with albuminuria. To maintain kidney and cardiovascular benefits, dosage adjustments may be necessary for those with decreased kidney function or who take UGT enzyme inducers.
